For me, a lot of it depends on if I am a GM or a PC. That said, I can't think of a genre I would shy away from. Not that it doesn't exist, but I can't think of one.
As a player, I tend to play in:
- Fantasy (High and Low)
- Urban Fantasy/Horror
As a GM though, I tend to run...
- High Fantasy
- Space Opera
- Super Hero
That said, I've run - and played - in the occasional cyberpunk, western, and other games. I'm rather loving the Dark Fantasy/Horror Shadows of Esteren game I'm in right now, and I can't wait to get my hands on 7th Sea for some Swashbuckling Adventure!
What about you? What genres do you find yourself in? What genres would you like to make your way over to?